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Coeliac disease is an autoimmune condition caused by gluten intolerance in those individuals who are genetically susceptible. Coeliac disease affects approximately 1% of the European population and results in damage to the lining of the gut. Symptoms of coeliac disease include diarrhoea, weight loss, pain and vomiting. If a gluten-free diet is not strictly followed, nutrient deficiencies can occur. On a standard gluten-free diet, approximately 80% of overweight coeliac patients will gain weight and 30% of normal weight coeliac patients will become overweight.A study was carried out to assess the effect of a strict gluten-free diet on nutritional status of coeliac patients and healthy controls. Fifteen coeliac patients and fifteen healthy controls were recruited and followed a 6-month gluten-free diet. Blood samples were taken at baseline (before the diet) and 6-months later (after the diet) and used to assess iron, folate and vitamin B12 status. Body mass index (BMI) was also recorded before and after the diet intervention.
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